About Non-Invasive Prenatal Testing (NIPT)

As the baby grows in the mother’s womb, a small amount of the baby’s DNA will enter the mother’s bloodstream. NIPT is a non-invasive blood test that able to screen the baby’s DNA for certain abnormalities caused by extra or missing chromosome material.

 

A Non-invasive Blood Test That Screens For Common Chromosomal Abnormalities
As Early As 10th Week Of Gestation.

Up to 18 Conditions Can Be Tested By StemLife NIPT

Trisomies
  1. T21 (Down Syndrome)
  2. T18 (Edwards Syndrome)
  3. T13 (Patau Syndrome)
  4. Trisomy 22
  5. Trisomy 16
  6. Trisomy 9
Sex Chromosomes
  1. Monosomy X (Turner Syndrome)
  2. Trisomy X (Triple X)
  3. XXY (Klinefelter Syndrome)
  4. XYY (Jacob’s Syndrome)
Microdeletions syndrome
  1. 1p36 deletion
  2. 2q33.1deletion
  3. 4p16.3 (Wolf-Hirschhorn Syndrome)
  4. 5p- deletion (Cri-du-chat Syndrome)
  5. 7q11.23 deletion
  6. 11q23 deletion (Jacobsen syndrome)
  7. 15q11.2 deletion (Angelman/Prader-Willi Syndrome)
  8. 22q11.2 deletion (DiGeorge syndrome)
Disclaimer
No test is perfect. DNA test results do not provide a definitive genetic risk in all individuals. Cell-free DNA does not replace the accuracy and precision of prenatal diagnosis with CVS or amniocentesis. Patients with positive test result or an additional finding should be referred for genetic counselling and offered invasive prenatal diagnosis for confirmation of test results. A negative test result does not ensure an unaffected pregnancy. The absence of an additional finding does not indicate a negative result. While results of this testing is highly accurate, not all chromosomal abnormalities may be detected due to placental, maternal or fetal mosaicism, or other causes. The healthcare provider is responsible for the use of this information in the management of their patient.


Reference :
1) Screening for fetal aneuploidy. Practice Bulletin No. 163. American College of Obstetricians and Gynecolo-gists. Obstet Gynecol. 2016;127: e123–37.

^ It is only applicable to all the chromosomal abnormalities as stated above except microdeletion syndromes.